Description

Efudix Cream is used to treat skin conditions such as growths of the skin (keratoses) and some simple skin cancers. The active ingredient fluorouracil belongs to a group of anti-cancer medicines.

Important Information about How Efudix Works
Efudix destroys cancerous and pre-cancerous cells, while having little effect on normal cells. When you use Efudix it is likely that the area of the skin that you are treating will become red. This will probably be followed by inflammation/ swelling, possibly some discomfort, skin erosion and eventually, healing. This is the expected normal response to treatment and shows that Efudix is working.

What you need to know before you use Efudix Cream
Do not use Efudix Cream:
• if you are allergic to fluorouracil or any other ingredients in this medicine
• if you are pregnant, think you may be pregnant, or are breast-feeding.
• if you are using any medicines known as antiviral nucleosides (e.g. brivudine,
sorivudine).
These medicines are usually used to treat chickenpox or shingles.

Warnings and precautions
Talk to your doctor or pharmacist before taking Efudix Cream:
• if you know that you have reduced or no activity of the enzyme dihydropyridine
dehydrogenase (DPD) (partial or complete DPD deficiency).

Efudix Cream is not for use in anyone under 18 years of age.

Other medicines and Efudix Cream
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. This is very important, as using more than one medicine at the same time can strengthen or weaken the effect of the medicines involved.

In particular, tell your doctor if you are using:
• medicines to treat chickenpox or shingles (brivudine, sorivudine) or have used them in
the last 4 weeks. These medicines may increase the possibility of unwanted effects with
Efudix Cream.